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RU58841 Powder: 3 grams
Molecular Formula: C17H18F3N303
Purity: >99% (See test reports here)
Each unit comes with a calibrated dropper with 0.25, 0.50, 0.75 and 1.0 ml marks
3 Grams for $45 (equivalent to 5 grams for $75, or $15 per gram). 3x3gram package is also offered for $105 ($11.6 per gram).
Three (3) grams of RU58841 is packed in a 60 ml bottle for convenient usage. FYI, Dissolving the whole 3 grams in a 60 ml solvent makes a 5% solution. The bottle is made of HDPE plastic that is resistant to most common solvents. It does not break during shipping like glass bottles.
The RU58841 powder can be dissolved in any minoxidil products we offer to make a minoxidil & Ru58841 combo. How to do it? Pour 60 ml minoxidil products to the bottle with 3 grams of RU58841 and shake the bottle until all powder is dissolved.
The bottle is air-tight sealed to prevent any moisture for long time storage.
When 9 gram option is selected, you will receive 3 bottles, each containing 3 grams of RU-58841 powder.
Storage temperature: ≤ 25o (no higher than 25 Celsius degree).
For your convenience, we have premade RU58841 solution available. Check it out here.
If you want to make your own solution, we also offer PG Sovent and PG Free Solvent which can be used to dissolve this material.
What is RU58841?
It is a nonsteroidal anti-androgen (NSAA). Its structure is shown below. It was investigated and developed by ProStrakan for its potential therapeutic applications in conditions that were driven by androgens. Conditions, such as acne, hirsutism (excessive hair growth), and androgenetic alopecia. ProStrakan conducted two clinical studies, phase I and II, and the results of 5% RU-58841, when applied twice daily, were reported to stimulate hair growth.
How does it work?
As a non-steroidal anti-androgen, RU binds itself to androgen receptors and directly inhibits the effects of endogenous (from our own body) androgens such as testosterone and dihydrotestosterone (DHT). As a first generation non-steroidal anti-androgen, it selectively competes for the androgen receptors. This competition effectively attenuates the activity of testosterone and DHT, leading to an overall anti-androgen effect.
The way it works is similar to that of spironolactone, and ketoconazole, a key ingredient used in hair loss shampoo.
It differs from finasteride or dutasteride, which inhibits the activity of 5α-Reductase, an enzyme that converts testosterone into dihydrotestosterone (DHT). DHT is the primary hormone that causes hair loss in men. See the figure below.
Based on the mechanism, it is apparent that finasteride and dutasteride may lead to a decreased DHT level, while RU58841 does not. DHT is pivotal to a male's sexual functionality, that is reason why some people choose RU instead of finasteride. This is also why more people are using topical finasteride instead of oral form to avoid its systemic effect (lowering DHT on the scalp instead of the whole body).
The chemical is intended for research purposes only. This research compound is not approved by the FDA. We strongly advise you to familiarize yourself with it before any handling process. Misapplication of the product can be hazardous.
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