DualGen-10 has Minoxidil 10.0% with Azelaic Acid 5.0%, which has a good balance between hair regrowth and convenience. This product is also called DualGen-10 with PG because it has propylene glycol. The amount of minoxidil in this product is 2 times of that in Rogaine foam or Rogaine extra strength topical solution. In addition, a natural DHT blocker,Azelaic Acid , is added to this product. Do not use ualGen-10 if you are known to be allergic to propylene glycol. It is recommended to use this product twice daily with at least 8 hours apart between the two applications. Alternatively, this product can be used in conjunction with a lower strength minoxidil solution (such as, DualGen-5, or EssenGen-5). In this case, you will use DualGen-10 once daily and the lower strength minoxidil solution once daily as well. The two applications should be at least eight hours apart.
Azelaic acid: 5%
ABN complexTM: 0.8%
Two large scale clinical studies compared the efficacy of 5% minoxidil and 2% minoxidil, one for male hair loss and the other for female hair loss. In both studies (~400 subjects), people were either give 5% minoxidil, 2% minoxidil, or placebo twice daily.
Results after 48 weeks (~1 year) showed 5% minoxidil offered much better results than 2%, and 2% minoxidil offered better results than 2%. "In men with AGA (androgenic alopecia or male/female pattern baldness), 5% topical minoxidil was clearly superior to 2% topical minoxidil and placebo in increasing hair regrowth, and the magnitude of its effect was marked (45% more hair regrowth than 2% topical minoxidil at week 48). Men who used 5% topical minoxidil also had an earlier response to treatment than those who used 2% topical minoxidil. Psychosocial perceptions of hair loss in men with AGA were also improved. " Topical minoxidil (5% and 2%) was well tolerated by the men and women in the two clinical trials without evidence of systemic effects.
These trials clearly shows hair regrowth is dosage dependent. The higher minoxidil strength is, the better hair regrowth is.
Will 10% minoxidil give twice as much as regrowth of 5% minoxidil? Most likely it won't.
Will the higher concentration have higher side effects? Most side effects of minoxidil such as scalp itchiness or rashes are not caused by minoxidil itself, but by delivery vehicles such as alcohol or propylene glycol. These sides effects won't be increased.
The minoxidil caused side effects may be increased but should be well tolerated because minoxidil has to have a serum concentration of 20 ng/mL to have any hemodynamic or other systemic effect in the human body. Large clinical studies involved with thousands patients showed a 2% minoxidil solution resulted in 0.6 ng/ mL and a 5% minoxidil solution resulted in 1.2 ng / mL of minoxidil in the serum. So, there is more than a 16-fold safety margin from the use of 5% topical minoxidil, and 8-fold safety margin with the use of a 10% topical minoxidil solution assuming the serum concentration is doubled when the topical minoxidil is increased from 5% to 10%. In reality, the serum concentration should be less double. Thus the safety margin is more than 8-fold.
Question: It seems that you have only 10% minoxidil with 5% azelaic acid compounded with propylene glycol (PG), how can I get minoxidil 10% with azelaic acid 5% compounded without PG?
Answer: Dualgen-10 is compounded with propylene glycol (PG). We don't have equivalent product without PG (PG). If you are allergic to PG and wish to have the product without PG, you can buy Dualgen-15 NO PG and Dualgen-5 NO PG and mix them together. If you mix 2 oz of Dualgen-15 NO PG and 2 oz Dualgen-5 NO PG, you will get 4 oz Dualgen-10 NO PG.
(see more details here to find out how you can make minoxidil 10% with azelaic acid 5% without PG in 10 seconds).
Question: Can you offer your minoxidil 10% on Amazon or Ebay?
Answer: All products are exclusively available on our site. None of the high strength minoxidil such as 15% minoxidil, 10% minoxidil is offered on third party platform like Amazon, Ebay, Walmart, or CVS, etc.
You can use the Max Roller System 2 to 3 times a week to increase the effecacy of any minoxidil products including this product.
This is for men only product. Women should never use this product. People with any heart disease, or low or high blood pressure should not use this product. For general side effects of minoxidil product including 10% minoxidil , please read minoxidil side effects.